Risk factors of Chronic Kidney Disease (CKD)

Who is at risk?

Chronic kidney disease (CKD) can affect anyone, at any age, but the disease is most commonly found in those over age 60 years. Other risk factors include a family history of CKD, high blood pressure, cardiovascular disease, obesity, autoimmune disease, and urinary tract infections.

Although CKD can be caused by primary disease of the kidneys, it is most often diagnosed as secondary to diseases such as diabetes, hypertension, HIV, and lupus. People currently living with these diseases need to be mindful that they are at risk for developing kidney disease and should be regularly examined by a health care professional to monitor kidney function.

Chronic conditions that may lead to CKD

  • Diabetes is the disease most often associated with CKD. Over time, elevated blood glucose can impair blood flow to the kidneys, causing damage. People with both type 1 diabetes and type 2 diabetes are at high risk for CKD and should be tested regularly.Chronic Kidney Disease Risk Factors
  • Hypertension: Uncontrolled high blood pressure can cause kidney damage over time.
  • Atherosclerosis is hardening of the arteries and the formation of plaque in the arteries that supply blood to the kidneys. This results in ischemic nephropathy (inadequate blood flow to the kidneys), which can lead to progressive kidney damage.
  • Glomerulonephritis causes inflammation and damage to the kidney filtration system and can result in kidney failure. Glomerulonephritis can be caused by lupus and from infections that follow injury or surgery.
  • Obstruction: An enlarged prostate often obstructs the flow of urine and may therefore cause kidney stones.
  • Polycystic kidney disease is a hereditary disease that may cause cysts in both kidneys.
  • Analgesic nephropathy: Long-term use of analgesics such as acetaminophen (Tylenol®) and ibuprofen (Motrin®, Advil®) may cause CKD.
  • Other causes: HIV infection, sickle cell anemia, heroin abuse, amyloidosis, chronic kidney infections, and certain types of cancer can also cause CKD.

Reversible factors contributing to CKD

It is possible that the following components of renal insufficiency can be reversed especially in older persons (over 70 years) and in children:

  • Dehydration
  • Renal injury due to nephrotoxic agents such as acetaminophen and nonsteroidal analgesics
  • Obstruction, especially chronic prostate enlargement and strictures
  • Reduction of blood pressure to 130/80 mm Hg or better

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Note: The statements on this website and the products offered have not been evaluated by the US Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Contents herein are being provided solely for the purpose of information. If you are pregnant, do not take any of our products listed herein. Also, please consult your physician or a qualified medical professional prior to taking this or any other dietary supplements or if you feel you have uremic, metabolic or related health conditions. 

Chronic Kidney Disease Risk Factors